The fat cells have been crushed and filtered out and what remains is a liquid that contains a high concentration of stem cells.

Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through cell division) to produce more stem cells. Stem cells are very important in the regeneration of damaged tissues.


  • Very long lasting effect.
  • A completely natural material.
  • Day surgery, minimal discomfort and a short recovery.
  • Minimally invasive, with a low risk of complications.
  • Small scars at the donor site and no additional scars at the recipient site.
  • Improvement at both the recipient site and the area from where fat is harvested.


  • Surgical procedure is necessary with some discomfort involved in extracting fat from the donor site.

How does nanofat work?

First a fat graft has to be taken from anywhere on your body, mostly the belly or the inside of your upper legs. Next this fat will be washed with saline, filtered and then injected superficially into the skin with multiple injections all over the area that needs to be treated with a 27G (very thin) sharp needle.

What can nanofat injection do for you?

  • Nanofat has shown to have a beneficial, rejuvenating effect on ageing or damaged (sun-damage, discolorations) skin. Cells within the fat grafts are capable of “repairing” damaged tissue and presumably they stimulate the skin cells to produce substances that improve skin elasticity and deposition of essential structural proteins.
  • It also has a positive effect on scars making them less visible. Especially in combination with croton oil peeling and SNIF (sharp needle intracutaneous fat injection) we have seen very impressive results.

Who is a good candidate for nanofat injection?

  • Any person that has a damaged or aged skin. The person should have enough fat available to make the nanofat (from just a few milliliters for small areas to 30 – 40ml of nanofat for a whole face).
The areas where nanofat injection is used most:
  • Face
  • Hands
  • Décolletage

Who is not a good candidate for nanofat injection?

  • People suffering of anorexia or athletes where no fat at all can be found for grafting.

How to prepare for nanofat injection?

There is no specific preparation for this procedure.

How is nanofat injection performed?

  • Nanofat injection is usually performed under local anaesthesia. Only if it is combined with other procedures it will be done in general anesthesia.
  • The donor site is always infiltrated with a mixture of local anesthesia and adrenaline to reduce post-operative discomfort and bruising.
  • Liposuction—The fat can be taken by means of liposuction from any part of the body having a sufficient amount of fat, in most cases from the abdomen or the upper legs, but it can also be taken from the inner aspect of the knee, the thigh, the buttock or love handles.
  • After injecting local anesthesia, which minimizes bleeding in this particular area, a very small incision is made and fat is aspirated using a blunt needle with multiple perforations and a special aspirator. The small incision is closed with one dissolvable stitch.
  • Filtration—This fat is washed and filtered to separate blood, oil and local anesthetic from the fat cells.
  • Emulsification of the fat is achieved by shifting the fat 30 times between two 10-cc syringes connected to each other by a special connector.
  • Injection of the nanofat—If it’s done in local anesthesia recipient area is injected with a minimal amount of local anesthesia after which the fat cells are injected with a 27G (very fine) needle or a syringe. If it’s done in general anesthesia no local anesthetic will be injected as it has been observed that the local anesthetic has a negative effect on the survival rate of the injected fat.
  • MAFT-gun—For the injection of the fat we use the MAFT-gun. This is an innovative instrument developed in Taiwan by Dr Lin. It allows the steady, accurate and precise injection of the fat in very small drops. As opposed to microfat, the effect of nanofat usually appears with a delay of 4 weeks to 3 months.

What is the average treatment plan of nanofat?

As stand alone treatment it will be done as an outpatient procedure.

What to expect and do during the recovery period after nanofat injection?

  • Swelling—This procedure as stand-alone procedure causes hardly any swelling, bruising or discomfort

What are the risks of nanofat injection?

So far  no infections, fat cysts, granulomas, or other unwanted side effects were observed.

How long can I expect the results of nanofat to last?

The procedure is too new to give a sensible answer to that question.

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